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Senior Biologist, Immuno-oncology

Blueprint Medicines, headquartered in Cambridge, MA, is a top-tier, publicly-traded (BPMC) company focused on discovering, developing and commercializing highly-selective kinase inhibitors for genomically defined diseases.  The company has built a sophisticated genomics platform and one-of-a-kind annotated compound collection which is delivering a pipeline of novel therapies.  In just four years, five programs have been established in genomically defined cancers and one program in the rare genetic disease space.

Are you looking to join a collaborative group that is focusing on immuno-oncology and looking at new ways to attack tumors?    We have an amazing opportunity for an innovative and highly motivated senior level biologist with experience in immunology and cancer biology, and specific experience in immuno-oncology, to provide leadership and mentorship to our growing  immuno-oncology drug discovery group.  In this role, you will leverage your immunology and cell and molecular biology expertise to help set the strategy for our small molecule drug discovery programs that lead to the identification of drug candidates for clinical development.  This is a unique opportunity to join and mentor a learning oriented group at a clinical-stage company and make a significant impact as we become a fully commercialized biopharmaceutical organization. 


  • Set the strategy for and provide broad strategic and technical leadership across multiple immuno-oncology programs and initiatives
  • Leverage knowledge of immunology and cancer biology to explore the function of kinases in immune signaling with an emphasis on immuno-oncology but also inflammation and autoimmunity
  • Contribute to the identification and characterization of small molecule inhibitors of target immuno-kinases, including molecular definition of potential responders
  • Extend and diversify internal immunology capabilities through interaction with external collaborators and CROs
  • Play a leadership role on our Roche collaboration


  • PhD in immunology, biology or a related discipline
  • Immuno-oncology experience is a must and small molecule experience is preferred
  • Post-doctoral training
  • 5+ years of relevant industry experience in a biopharmaceutical setting
  • A strong publication record in the areas of inflammation, autoimmunity and/or immuno-oncology.
  • Strong interpersonal and communication skills and enthusiasm for participating in a fast-paced environment characterized by rigorous science and innovative thinking
  • Extensive experience with immune cell model systems and standard immunology techniques


  • Demonstrated application of immunology expertise to drug discovery efforts, preferably in support of immuno-oncology programs
  • Demonstrated experience providing leadership and mentoring to a strong multi-disciplinary team
  • Demonstrated experience working with contract research organizations and academic collaborators
  • Thrives in a results-driven, highly accountable environment where you can make a clear impact
  • A team player, who listens effectively and invites response and discussion
  • A collaborator who communicates in an open, clear, complete, timely and consistent manner 

All applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.


Blueprint Medicines’ mission is to dramatically improve the lives of patients with genomically defined diseases. Our singular focus is to use our deep understanding of the genetic blueprint of cancer and other diseases driven by the abnormal activation of kinases to craft highly selective medicines aimed at eradicating these diseases.

We don’t think in small steps. We think in giant leaps.

We are driven by the pursuit of new ideas, new innovations, and new ways of thinking.

We know that what each and every one of us does matters and that our success depends on our ability to work together. We believe we are at our best as a company when our employees are thriving and foster a culture that provides opportunities to grow and develop professionally, while also having fun.

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