View Our Website View All Jobs

Director, Computational Biology and Bioinformatics

Blueprint Medicines is seeking a versatile and enthusiastic scientist to lead Computational Biology and Bioinformatics. This individual will be responsible for computational strategies supporting our entire research and development pipeline of oncology and immunotherapy programs. The ideal candidate is a proven project leader who can influence stakeholders via his/her technical knowledge, innovative approaches and strategic thinking. Candidates must be collaborative and enjoy a fast-paced and hands-on research environment.


  • Provide strategic and scientific leadership to cross-functional research, translational medicine and clinical teams.
  • Direct activities related to data generated by high-throughput molecular assays and next-generation sequencing technologies with the goal of exploring novel therapeutic hypotheses, target identification and biomarker discovery.
  • Lead genomic analyses of tumor tissue and cell-free DNA samples obtained from clinical trials to refine therapeutic responder hypotheses.
  • Develop new approaches to continuously improve quality and success of computational initiatives.
  • Manage internal/external collaborations and contribute to assessment of strategic alliance opportunities.
  • Manage performance and development of scientific staff members for maximal success.
  • Present clearly and succinctly in a variety of internal and external settings.

Qualifications and core competencies:

  • Ph.D. degree in biology, bioinformatics, statistics or a related field.
  • Minimum 10 years of experience in computational biology and bioinformatics.
  • Deep understanding of computational methods, scripting and programming languages, and relevant concepts in cancer biology, immunology and/or genetics.
  • Demonstrated success in achieving key milestones and contributions to the field.
  • Excellent leadership capabilities with skill in building, guiding and motivating effective teams and fostering productive research collaborations.
  • Proven ability to hire, coach and develop world class talent.
  • Outstanding communication and partnering skills.

All applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.


Blueprint Medicines’ mission is to dramatically improve the lives of patients with genomically defined diseases. Our singular focus is to use our deep understanding of the genetic blueprint of cancer and other diseases driven by the abnormal activation of kinases to craft highly selective medicines aimed at eradicating these diseases.

We don’t think in small steps. We think in giant leaps.

We are driven by the pursuit of new ideas, new innovations, and new ways of thinking.

We know that what each and every one of us does matters and that our success depends on our ability to work together. We believe we are at our best as a company when our employees are thriving and foster a culture that provides opportunities to grow and develop professionally, while also having fun. 

Read More

Apply for this position

Apply with Indeed
Attach resume as .pdf, .doc, or .docx (limit 2MB) or Paste resume

Paste your resume here or Attach resume file

To comply with government Equal Employment Opportunity / Affirmative Action reporting regulations, we are requesting (but NOT requiring) that you enter this personal data. This information will not be used in connection with any employment decisions, and will be used solely as permitted by state and federal law. Your voluntary cooperation would be appreciated. Learn more.
Veteran/Disability status