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Senior Director, Software Architecture

Sr. Director, Software Architecture

Cambridge, MA


At Blueprint Medicines, as our name indicates, we are creating a blueprint for the future of healthcare.  We are a leading company in the personalized medicine revolution by focusing on delivering new medicines that are targeted to the genetic driver of disease.  We do this by leveraging our one-of-a-kind drug discovery platform to discover, develop and work to bring highly-selective kinase inhibitors to patients globally.  This prolific scientific platform has enabled Blueprint Medicines to build a pipeline of novel therapies that span three distinct areas of medicine; genomically defined cancers, rare diseases and cancer immunotherapy.


Job Summary:

This is an excellent opportunity for an experienced, hands-on, leader to help build Blueprint’s software development capabilities. This position will lead and grow a performance-driven software development team to develop new and innovative ways to bring information to our users and enable timely, data-driven decision-making. This position will report to the VP of Information System. Join our team and help us make a positive impact on cancer patients lives!


  • Lead and grow a high performing, customer-focused web applications development team
  • Lead the planning, design, development, and testing of internal applications to support Blueprint’s research and development effort
  • Provide long-term strategic vision on internal application and deployment framework
  • Work with cross-functional team to plan project timeline and deliverables
  • Manage integration of internal and external commercial applications through single sign-on and web services
  • Mentor individual team members to ensure continuous learning and skills development
  • Ensure compliance with data security standards and regulations


  • Minimum 10 years of experience leading a software development team
  • Minimum 5 years of experience doing hands-on software design and development
  • Bachelor’s degree Computer Science, Computer Engineering, or related field
  • Must have strong desire to build high performing, scaleable, and secure solutions
  • Must enjoy working in a fast-paced and growing environment
  • Broad understanding of industry trends and new technology
  • Strong experience developing web-based applications in Java
  • Strong experience with relational databases such as Oracle and MySQL
  • Experience with natural language processing and machine learning technologies is a plus


  • Strong analytical and troubleshooting skills and ability to resolve problems independently
  • Strong understanding agile development methodologies
  • Strong project planning and people management skills
  • Proven ability to handle multiple priorities and communicate progress to stakeholders
  • Proven ability to successfully grow, lead, and mentor software development team
  • At home in a results-driven, highly accountable environment where you can make a clear impact
  • A team player, who listens effectively and invites response and discussion
  • A collaborator who communicates in an open, clear, complete, timely and consistent manner


All applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability or protected veteran status.



Blueprint Medicines’ mission is to dramatically improve the lives of patients with genomically defined diseases. Our singular focus is to use our deep understanding of the genetic blueprint of cancer and other diseases driven by the abnormal activation of kinases to craft highly selective medicines aimed at eradicating these diseases.

We don’t think in small steps. We think in giant leaps.

We are driven by the pursuit of new ideas, new innovations, and new ways of thinking.

We know that what each and every one of us does matters and that our success depends on our ability to work together. We believe we are at our best as a company when our employees are thriving and foster a culture that provides opportunities to grow and develop professionally, while also having fun.

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